Diagnostic and Prognostic Significance of S#{233}zaryCells in Peripheral Blood Smears From Patients With Cutaneous T Cell Lymphoma
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چکیده
Blood smears stained with Wright-Giemsa were obtained from 1 24 patients with pathologically confirmed cutaneous T cell lymphoma (CTCL). 70 patients with various other cutaneous disorders, and ten healthy adult volunteers. These were examined in a blinded fashion for atypical lymphocytes with cerebriform nuclei (CLs). which were characterized further according to cell diameter. CLs. compricing up to 1 5% of lymphocytes in smears, were observed in 20% of the patients with benign dermatitis. CLs, compricing up to 89% of lymphocytes in smears, were found in 22%. 30%, 50%. and 96% of patients with patch. plaque. tumor, and erythrodermic CTCL. respectively. Large-diemeter CLs (1 5 to 20 .tm) were observed only in smears from patients with CTCL. Total CL counts above 1 5 per 100 lymphocytes and/or the presence of large CLs occurred in 33 of 49 (67%) patients with erythrodermic disease and in
منابع مشابه
Diagnostic and prognostic significance of Sézary cells in peripheral blood smears from patients with cutaneous T cell lymphoma.
Blood smears stained with Wright-Giemsa were obtained from 124 patients with pathologically confirmed cutaneous T cell lymphoma (CTCL), 70 patients with various other cutaneous disorders, and ten healthy adult volunteers. These were examined in a blinded fashion for atypical lymphocytes with cerebriform nuclei (CLs), which were characterized further according to cell diameter. CLs, comprising u...
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